Orthostatic Grading Scale (OGS)
Five questions grading how much standing up costs you, scored 0–20
The Orthostatic Grading Scale was developed at the Mayo Clinic's autonomic laboratory by Schrezenmaier, Low, Sandroni and colleagues and published in 2005. It was designed to put a number on orthostatic intolerance in the way a clinician would take a history: how often symptoms happen on standing, how severe they are, what conditions bring them on, how much they interfere with daily activities, and how long you can stand before they start. Each of the five items scores 0–4, for a total of 0–20.
In the original study of 145 patients the scale was internally consistent (alpha 0.91) and tracked laboratory measures of adrenergic autonomic function. It has since been used in UK POTS research, ME/CFS studies, the CDC's multi-site ME/CFS study, and post-COVID cohorts. "Orthostatic symptoms" here means the symptoms you get on standing: lightheadedness, dizziness, blurred vision, weakness, fatigue, brain fog, palpitations, nausea, or feeling faint.
The OGS describes your usual pattern, which makes it a good baseline and monthly tracking measure. The Vanderbilt Orthostatic Symptom Score is the complementary snapshot rated while standing, the Malmö POTS score covers the past week, and the NASA lean test records the heart-rate data that a POTS or orthostatic hypotension diagnosis actually needs.
Your Orthostatic Grading Scale score
Item breakdown
Reference values
Understanding your score
The bands most often quoted are mild (below 4), moderate (4–9), and severe (above 9), from Frith and Newton's work on orthostatic symptoms. In the original Mayo data a score of 9 or more was the best match for laboratory evidence of adrenergic failure, with modest accuracy (66% sensitivity, 69% specificity), which is a reminder that symptom burden and measured autonomic function only partly overlap.
Published averages: healthy controls 0.6–3; UK POTS patients about 13 (SD 4); ME/CFS cohorts 8–13; hypermobile EDS about 10; post-COVID condition about 11. A 2023 UK study of people referred with suspected POTS found the five items behave as a single dimension and correlate with heart-rate responses on standing.
Because the OGS asks about your usual pattern rather than a single week, it changes slowly. Repeating it monthly, or before and after a treatment change, is enough. Record it with your stand test results so the symptom score and the heart-rate response sit together.
This is not a diagnosis. Discuss your results with your doctor or specialist.