Vanderbilt Orthostatic Symptom Score (VOSS)

Nine symptoms rated 0–10 while upright: the standing symptom score from POTS trials

The Vanderbilt Orthostatic Symptom Score comes from the Vanderbilt Autonomic Dysfunction Center, where Satish Raj and colleagues used it in POTS drug studies from 2005 onwards. It has since been used in the Calgary compression garment trial, exercise studies in post-COVID POTS, and a growing list of others. You rate nine symptoms from 0 (absent) to 10 (the worst you have experienced) for how you feel right now. The total runs from 0 to 90.

Unlike the weekly Malmö POTS score or the broader COMPASS-31, the VOSS is a snapshot. In trials it is completed at the end of a 10-minute stand or tilt, which makes it a natural companion to the NASA lean test: rate your symptoms at the end of the standing phase and you have a symptom number to sit alongside the heart-rate numbers. Rated lying down and again after standing, the difference shows how much standing itself drives your symptoms.

This is not a diagnostic tool. The VOSS has no validated cut-off and no formal validation study; it is used in research as a change measure. Healthy people report symptoms after a prolonged tilt too, so a non-zero score is expected. It cannot tell POTS apart from other causes of orthostatic symptoms. Discuss your results with your doctor. Based on: Raj SR, Black BK, Biaggioni I, Harris PA, Robertson D. Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome. Circulation. 2005;111(21):2734–2740; and Raj SR, et al. Propranolol decreases tachycardia and improves symptoms in POTS: less is more. Circulation. 2009;120(9):725–734. Instruction wording on this page is our own; the score is described in those papers rather than distributed as a form.

When are you rating these symptoms?

Rate how severe each symptom is right now, where 0 = absent and 10 = the worst you have experienced.

Mental clouding (brain fog, difficulty thinking clearly)

Blurred vision

Shortness of breath

Rapid heartbeat

Tremulousness (shakiness)

Chest discomfort

Headache

Lightheadedness

Nausea